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首頁-技術(shù)文章-CEM微波合成用于Racemization的研究

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CEM微波合成用于Racemization的研究

更新時(shí)間：2012-06-29 點(diǎn)擊次數(shù)：2391

INTRODUCTION

One potential issue in peptide synthesis is racemization of cysteine and histidine. This is a concern for microwave peptide syntheis because of the elevated temperatures during deprotection and coupling. Studies have shown that lowering the temperature to 50 °C during the coupling of histidine and cysteine will decrease racemization.